Monasticism

Diversity in caves, mountains, and other structures for regular prayer and worship, especially used to store scrolls such as Monastery of Saint Anthony;
Mar Awgin founded a monastery on Mt. Izla above Nisibis in Mesopotamia (Persia); Armenia, Georgia and even India and China.
St. Sabbas the Sanctified organized the monks of the Judean Desert in a monastery close to Bethlehem (483), now known as Mar Saba, which is considered the mother of all monasteries of the Eastern Orthodox churches.
Saint Catherine's Monastery was founded between 527 and 565 in the Sinai Peninsula, Egypt. For more info see https://en.wikipedia.org/wiki/Degrees_of_Eastern_Orthodox_monasticism